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Probiotics & COVID-19:

Beyond gut health.

Probiotics have long been known to improve gastrointestinal health and modulate the immune system. These compete for nutrients and receptors against pathogenic microorganisms and exert antimicrobial activity, activate the immune response and lower the pro-inflammatory response. A balanced gut microbiome is critical as made evident by diseases such as diabetes, cancer, cardiovascular or neurological disorders.


Over 1000 microbial species compose our gut microbiome, varying vastly from individual to individual. Since COVID-19 pandemic was declared, some evidence has emerged suggesting that the use of probiotics could ameliorate COVID-19 related GI symptoms, as well as playing a role in the prophylaxis of this viral disease. In addition, it has also been suggested that COVID-19 symptoms could vary depending on the gut microbiome composition.

  • Probiotics could reduce the duration of specific respiratory tract viral infections.

  • Probiotics lower the pro-inflammatory response, preventing the onset of a cytokine storm
    which ultimately lead to acute lung injury (ALI).

  • Probiotics reinforce gut immunity, reducing COVID-19 GI manifestations.


Live probiotics are under debate due to that it could put vulnerable populations at risk due to potential bacterial translocations. Tyndallized probiotics are an interesting alternative.

  • Patented.

  • Highly stable, even in liquid formulations.

  • High safety profile.

  • Exert specific immunomodulatory effects and reduce GI symptoms.

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Probiotic supplementation exert immunomodulatory and antiviral effects which may partially halt COVID-19 development and symptoms. Tyndallized probiotics are a safe alternative to reinforce the immune system of the most vulnerable populations. Although further research is needed in the future, probiotics could be considered as a coadjuvant option for the prophylaxis of Corona viral diseases, including COVID-19.


Hao Q, Dong BR, Wu T. (2015) Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev CD006895

King S. et al (2014) Effectiveness of probiotics on the duration of illness in healthy children and adults who develop common acute respiratory
infectious conditions: a systematic review and meta-analysis. Br J Nutr 112: 41–54

Prince CP (2020) A comprehensive review of probiotics and their uses for control of viral infections in the wake of pandemic COVID-19. Tropical
Journal of Pharmaceutical and life Sciences. 7(2): 1-14

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